Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationship between chronic inflammatory diseases and uveal melanoma: A bidirectional Mendelian randomization study.

Indian journal of ophthalmology - 1 Nov 2025

Wang Yanbing, Tan Yao, Chen Zhaochangci, Yin Jiayang

Abstract excerpt

PURPOSE: This study aimed to investigate the causal relationship between chronic inflammatory diseases and uveal melanoma (UVM) and to elucidate the underlying molecular mechanisms and clinical implications. METHODS: In this bidirectional Mendelian randomization (MR) study, we analyzed the causal relationships between nine common chronic inflammatory diseases and UVM using summary-level genome-wide association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Melanoma

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Uveal Melanoma

Share to Uveal Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41148015
DOI: 10.4103/IJO.IJO_536_25
PMCID: PMC12659841

Genes

CARD9
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationship between chronic inflammatory diseases and uveal melanoma: A bidirectional Mendelian randomization study.PMID 41148015Read ↗

Association between inflammatory factors and melanoma: a bidirectional Mendelian randomization study.Semantic proximity Read ↗

Causal Relationship Between Inflammatory Bowel Disease and Malignant Melanoma: A Mendelian Randomization AnalysisSemantic proximity Read ↗

Immune cells mediate the causal relationship between uveitis and colorectal cancer via Mendelian randomization analysis.Semantic proximity Read ↗

Causal relationship between inflammatory factors and inflammatory bowel disease: A bidirectional Mendelian randomization study combined with meta-analysis.Semantic proximity Read ↗

The Genetic Causal Effect of Autoimmune Diseases on pan-Cancers: Evidence from Mendelian RandomizationSemantic proximity Read ↗

Unraveling the causal association between inflammatory bowel diseases and uveitis through mendelian randomization analysisSemantic proximity Read ↗

Integrative Mendelian Randomization and Transcriptomic Analysis Reveal the Causal Association between Psoriatic Arthritis and Uveitis.Semantic proximity Read ↗

Celiac Disease and Skin Diseases: A Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

Unraveling the Causal Links and Novel Molecular Classification of Crohn’s Disease in Breast Cancer: A Two-Sample Mendelian Randomization and Transcriptome Analysis with Prognostic ModelingSemantic proximity Read ↗

Causal role of immune cells in uveitis: Mendelian randomization study.Semantic proximity Read ↗

Association between inflammatory bowel disease and the risk of parenteral malignancies: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Immune-Mediated Bidirectional Causality Between Inflammatory Bowel Disease and Chronic Periodontitis: Evidence from Mendelian Randomization and Integrative Bioinformatics AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.