Article

Integrative Machine Learning and Bioinformatics Analysis to Identify Cellular Senescence-Related Genes and Potential Therapeutic Targets in Ulcerative Colitis and Colorectal Cancer

2025-03-27

Abstract excerpt

<h4>Background</h4> Ulcerative colitis (UC) is a chronic inflammatory condition that predisposes patients to colorectal cancer (CRC) through mechanisms that remain largely undefined. Given the pivotal role of cellular senescence in both chronic inflammation and tumorigenesis, we integrated machine learning and bioinformatics approaches to identify senescence□related biomarkers and potential therapeutic targets in...

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Literature Corpus work: 59c80e4e-c141-570b-8304-402b1a0586ad
DOI: 10.1101/2025.03.24.644876

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