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Screening of key genes related to M6A methylation in patients with heart failure.

BMC cardiovascular disorders - 16 Oct 2024

Wu Zelan, Liu Wupeng, Si Xiaoyun, Liang Jinfeng

Abstract excerpt

OBJECTIVE: This study aims to identify m6A methylation-related and immune cell-related key genes with diagnostic potential for heart failure (HF) by leveraging various bioinformatics techniques. METHODS: The GSE116250 and GSE141910 datasets were sourced from the Gene Expression Omnibus (GEO) database. Correlation analysis was conducted between differentially expressed genes (DEGs) in HF and control groups,...

Topics

Humans
Heart Failure
Databases, Genetic
Gene Expression Profiling
Gene Regulatory Networks
Case-Control Studies
Adenosine
Computational Biology
Transcriptome
Male
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reproducibility of Results

Predictive Value of Tests

Genetic Markers

Middle Aged

Aged

Gene Expression Regulation

Methylation

Source

Open in PubMed Open full text

Identifiers

PMID: 39415091
DOI: 10.1186/s12872-024-04228-9
PMCID: PMC11481427

Genes

HBA1
LACTB2
NAMPT
SCAMP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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