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Basal and AT2 cells promote IPF-lung cancer co-occurrence via EMT: Single-cell analysis

26 Apr 2025

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung disease. With IPF, the probability of complication with lung cancer (LCA) increases considerably, and the prognosis is worse than that of simple IPF. To understand the pathological mechanisms and molecular pathways shared by these two diseases, we used the single-cell analysis from the Gene Expression Omnibus (GEO) database,...

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PMID: 40294812
DOI: 10.1016/j.yexcr.2025.114578

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