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Weighted Gene Co-expression Network Analysis Identifies a Cancer-Associated Fibroblast Signature for Predicting Prognosis and Therapeutic Responses in Lung Squamous Cell Carcinoma

2023-01-27

Abstract excerpt

<h4>Background: </h4> Cancer-associated fibroblasts (CAFs) are vital in tumorigenesis, metastasis, and response to therapy. This study aimed to explore the characteristics of CAFs in lung squamous cell carcinoma (LUSC) and to develop a CAF-based risk signature for predicting the prognosis of this disease. <h4>Methods: </h4>: The mRNA expression and clinical information of 235 LUSC samples were obtained from the G...

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Literature Corpus work
0be19a25-8e42-5f77-b94e-c55fa6e59b87
DOI
10.21203/rs.3.rs-2506728/v1
Open publication

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