Identification of common signatures in idiopathic pulmonary fibrosis and lung cancer using gene expression modeling

Abstract excerpt

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is associated with an increased risk for lung cancer, but the underlying mechanisms driving malignant transformation remain largely unknown. This study aimed to identify differentially expressed genes (DEGs) distinguishing IPF and lung cancer from healthy individuals and common genes driving the transformation from healthy to IPF and lung cancer. METHODS: The gene...

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