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Acid-resistant chemotactic DNA micromotors for probiotic delivery in inflammatory bowel disease

22 Apr 2025

Abstract excerpt

Microcapsules composed of synthetic polymeric matrices have attracted considerable attention in delivering oral probiotics. However, existing polymeric microcapsules demonstrate inadequate acid resistance and adaptability, as well as deficiency in the inflamed colon-specificity and uncontrolled release of probiotics therein. Herein, a DNA microcapsule is prepared as a probiotic-transporting micromotor through...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 40263286
DOI: 10.1038/s41467-025-59172-9

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