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Association of MTHFR Gene with Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis.

Public health genomics - 1 Jan 2025

Huang Qian, Chang WeiWei, Wang YuanYuan, Zhang HeQiao, Zhou JiaMou, Shen HuiYan, Yang LinSheng, Zhang DongMei, Chen GuiMei

Abstract excerpt

INTRODUCTION: Multiple studies have shown that genetic polymorphism in the MTHFR gene is associated with susceptibility to type 2 diabetes mellitus (T2DM), but the results remain controversial. This study was divided into two parts. The first part was to explore the relationship between the SNPs of MTHFR gene (C677T and A1298C) and genetic susceptibility to T2DM. Second, a meta-analysis was performed to evaluate...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Identifiers

PMID: 40258351
DOI: 10.1159/000545731

Genes

MTHFR

Variants

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Association of MTHFR Gene with Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis.PMID 40258351Read ↗

Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism and type 2 diabetes mellitus in Chinese population: a meta-analysis of 29 case-control studies.Semantic proximity Read ↗

Meta-analysis of MTHFR C677T polymorphism and type 2 diabetes mellitus in MENA region.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase A1298C polymorphism and diabetes risk: evidence from a meta-analysis.Semantic proximity Read ↗

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The MTHFR C677T/A1298C polymorphism is associated with increased risk of microangiopathy in type 2 diabetes mellitus: A systematic review and meta-analysis.Semantic proximity Read ↗

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