Article
Association of the C677T polymorphism in the human methylenetetrahydrofolate reductase (MTHFR) gene with the genetic predisposition for type 2 diabetes mellitus in a Moroccan population.
Genetic testing and molecular biomarkers - 1 May 2012
Benrahma Houda, Abidi Omar, Melouk Leila, Ajjemami Maria, Rouba Hassan, Chadli Asmaa, Oudghiri Mounia, Farouqui Ahmed, Barakat Abdelhamid
Abstract excerpt
AIMS: Type 2 diabetes mellitus (T2DM) is a major public health problem around the world. The C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene have been reported to be associated with T2DM and its complications. This study aimed to investigate this association in the Moroccan population. METHODS: A case-control study was performed among 282 Moroccan diabetic patients and 232...
Topics
- Aged
- Case-Control Studies
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)