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Article

Methylenetetrahydrofolate reductase gene polymorphism and risk of type 2 diabetes mellitus.

PloS one - 1 Jan 2013

Zhong Jian-Hong, Rodríguez A Chapin, Yang Na-Na, Li Le-Qun

Abstract excerpt

OBJECTIVE: This review aimed to comprehensively assess the literature examining a possible link between the rs1801133 polymorphism (677C → T) in the gene encoding the methylenetetrahydrofolate reductase (MTHFR) gene and risk of type 2 diabetes mellitus (DM). RESEARCH DESIGN AND METHODS: Several research databases were systematically searched for studies examining the genotype at the rs1801133 polymorphism in...

Topics

Case-Control Studies
Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Humans
Methylenetetrahydrofolate Reductase (NADPH2)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 24023947
DOI: 10.1371/journal.pone.0074521
PMCID: PMC3762795

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24023947-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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