Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase gene polymorphism and risk of type 2 diabetes mellitus.

PloS one - 1 Jan 2013

Zhong Jian-Hong, Rodríguez A Chapin, Yang Na-Na, Li Le-Qun

Abstract excerpt

OBJECTIVE: This review aimed to comprehensively assess the literature examining a possible link between the rs1801133 polymorphism (677C → T) in the gene encoding the methylenetetrahydrofolate reductase (MTHFR) gene and risk of type 2 diabetes mellitus (DM). RESEARCH DESIGN AND METHODS: Several research databases were systematically searched for studies examining the genotype at the rs1801133 polymorphism in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Case-Control Studies

Share to Diabetes Mellitus, Type 2

Share to MTHFR gene

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 24023947
DOI: 10.1371/journal.pone.0074521
PMCID: PMC3762795

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase gene polymorphism and risk of type 2 diabetes mellitus.PMID 24023947Read ↗

Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.Semantic proximity Read ↗

Association of MTHFR Gene with Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase A1298C polymorphism and diabetes risk: evidence from a meta-analysis.Semantic proximity Read ↗

Relationship between MTHFR C677T and A1298C gene polymorphisms and complications of type 2 diabetes mellitus in an Emirati populationSemantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and diabetic nephropathy susceptibility in patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Association of tagging SNPs in the MTHFR gene with risk of type 2 diabetes mellitus and serum homocysteine levels in a Chinese population.Semantic proximity Read ↗

Association analysis of MTHFR (rs1801133 and rs1801131) gene polymorphism towards the development of type 2 diabetes mellitus in Dali area population from Yunnan Province, China.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphism and susceptibility to diabetic nephropathy in type 1 diabetes.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism and type 2 diabetes mellitus in Chinese population: a meta-analysis of 29 case-control studies.Semantic proximity Read ↗

Meta-analysis of MTHFR C677T polymorphism and type 2 diabetes mellitus in MENA region.Semantic proximity Read ↗

Association of methylene tetrahydrofolate reductase C677T genotype with type 2 diabetes mellitus patients with and without renal complications.Semantic proximity Read ↗

Association of ACE and MTHFR genetic polymorphisms with type 2 diabetes mellitus: Susceptibility and complications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.