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Article

MiR-1 alleviates chronic heart failure through HCN2/HCN4 axis in vitro

14 Apr 2025

Abstract excerpt

OBJECTIVE: Chronic heart failure (CHF) is a complex and progressive condition. This study aimed to investigate the potential regulatory effect of miR-1 on CHF through the hyperpolarization-activated cyclic nucleotide-gated channels 2 and 4 (HCN2/HCN4) axis. METHOD: The expression of miR-1 was examined in individuals diagnosed with CHF. The patients' level of NT-proBNP was evaluated. A cellular model using H9c2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40252568
DOI: 10.1016/j.tice.2025.102921

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