Article
A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2010
Lencz Todd, Szeszko Philip R, DeRosse Pamela, Burdick Katherine E, Bromet Evelyn J, Bilder Robert M, Malhotra Anil K
Abstract excerpt
ZNF804A is one of the strongest candidate genes for schizophrenia (SZ), yet its function and role in disease pathophysiology are largely unknown. The only in vivo endophenotype study of the SZ-associated SNP (rs1344706) pointed towards effects on brain functional connectivity. We examined the relationship of this SNP to neuroanatomical and neurocognitive phenotypes that were assessed in healthy individuals....
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