Article
Genetic polymorphism and neuroanatomical changes in schizophrenia.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2000
Năstase Mihai Gabriel, Vlaicu Ilinca, Trifu Simona Corina
Abstract excerpt
The article is a review of the latest meta-analyses regarding the genetic spectrum in schizophrenia, discussing the risks given by the disrupted-in-schizophrenia 1 (DISC1), catechol-O-methyltransferase (COMT), monoamine oxidases-A∕B (MAO-A∕B), glutamic acid decarboxylase 67 (GAD67) and neuregulin 1 (NRG1) genes, and dysbindin-1 protein. The DISC1 polymorphism significantly increases the risk of schizophrenia, as...
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