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Article

Genetic association of lipid and lipid-lowing drug targets with uterine fibroids

26 Dec 2024

Abstract excerpt

Objective: Observational studies suggest that blood lipids are a risk factor for uterine fibroids (UFs) and that lipid-lowering drugs are beneficial for the treatment and prevention of UF; however, the conclusions are inconsistent. We aimed to determine the causal effects of lipids and lipid-lowering drugs on UFs using Mendelian randomization (MR). Methods: Genetic variants from genome-wide association studies...

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PMID: 39844969
DOI: 10.1016/j.heliyon.2024.e41539

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