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Article

Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions.

Journal of the American Heart Association - 7 Mar 2023

Xiao Brenda, Velez Edwards Digna R, Lucas Anastasia, Drivas Theodore, Gray Kathryn, Keating Brendan, Weng Chunhua, Jarvik Gail P, Hakonarson Hakon, Kottyan Leah, Elhadad Noemie, Wei Wei-Qi, Luo Yuan, Kim Dokyoon, Ritchie Marylyn, Verma Shefali Setia

Abstract excerpt

Background Cardiometabolic diseases are highly comorbid, but their relationship with female-specific or overwhelmingly female-predominant health conditions (breast cancer, endometriosis, pregnancy complications) is understudied. This study aimed to estimate the cross-trait genetic overlap and influence of genetic burden of cardiometabolic traits on health conditions unique to women. Methods and Results Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36846987
DOI: 10.1161/JAHA.121.026561
PMCID: PMC10111435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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