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Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC

1 Apr 2025

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve and spread, and it remains critical to understand the functional consequences of mutations in dominant viral variants. The recombinant JN.1 subvariant XEC recently replaced KP.3.1.1 to become the most prevalent subvariant worldwide. Here, we measure the in vitro neutralization of KP.3.1.1 and XEC by human sera, monoclonal antibodies,...

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Identifiers

PMID: 40202847
DOI: 10.1016/j.celrep.2025.115543

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