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Article

Development and pilot testing of a prostate cancer polygenic risk report.

BMC medical genomics - 30 Jul 2026

Griffin Julia N, Danowski Morgan E, Gerety Haley L, Lafferty Katherine, Clayman Marla L, Antwi Ashley A, Bertero Mercedes G, Brunette Charles A, Gillespie Chris, Guentert Louise, Lennon Niall J, Martin Julian, Patel Lauren S, Vassy Jason L

Abstract excerpt

BACKGROUND: Polygenic risk scores (PRS) are increasingly being incorporated into clinical care, yet optimal strategies for communicating PRS results to patients and clinicians remain undefined. Effective report design is critical to ensure comprehension and appropriate use, particularly for complex conditions such as prostate cancer where screening decisions are nuanced. We developed and pilot tested...

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Identifiers

PMID: 42661205
DOI: 10.1186/s12920-026-02416-4
PMCID: PMC13520487

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