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Article

Effects of lithium on mortality and metabolite profiles in Drosophila lithium-inducible SLC6 transporter mutants.

Environmental toxicology and pharmacology - 1 Jun 2025

Kasuya Junko, Kruth Karina, Lee Dongkeun, Kim Jong Sung, Williams Aislinn, Kitamoto Toshihiro

Abstract excerpt

Lithium has long been the primary treatment for bipolar disorder and shows promise for managing other neurological and psychiatric conditions. We previously identified the Lithium-inducible SLC6 transporter (List) in Drosophila melanogaster as a gene significantly upregulated in response to lithium chloride supplementation. List encodes a putative amino acid transporter belonging to the Na⁺-dependent solute...

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Identifiers

PMID: 40194719
DOI: 10.1016/j.etap.2025.104684
PMCID: PMC12129673

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