Article
Drosophila TRPM channel is essential for the control of extracellular magnesium levels.
PloS one - 6 May 2010
Hofmann Thomas, Chubanov Vladimir, Chen Xiaodi, Dietz Anna S, Gudermann Thomas, Montell Craig
Abstract excerpt
The TRPM group of cation channels plays diverse roles ranging from sensory signaling to Mg2+ homeostasis. In most metazoan organisms the TRPM subfamily is comprised of multiple members, including eight in humans. However, the Drosophila TRPM subfamily is unusual in that it consists of a single member. Currently, the functional requirements for this channel have not been reported. Here, we found that the...
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