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Lithium can mildly increase health during ageing but not lifespan in mice

17 Sept 2021

Abstract excerpt

Lithium is a nutritional trace element, used clinically as an anti-depressant. Preclinically, lithium has neuroprotective effects in invertebrates and mice, and it can also extend lifespan in fission yeast, C. elegans and Drosophila. An inverse correlation of human mortality with the concentration of lithium in tap water suggests a possible, evolutionarily conserved mechanism mediating longevity. Here, we...

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PMID: 34532960
DOI: 10.1111/acel.13479

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