Comparison Between Antigen and Allelic HLA Mismatches, and the Risk of Acute Rejection in Kidney Transplant Recipients.

doi:10.1111/tan.70163

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Article

Comparison Between Antigen and Allelic HLA Mismatches, and the Risk of Acute Rejection in Kidney Transplant Recipients.

HLA - 1 Apr 2025

Gately Ryan, Taverniti Anne, Watson Narelle, Teixeira-Pinto Armando, Ooi Esther, Lalji Rowena, Francis Ross, Sullivan Lucy, Mulley William, Wyburn Kate, Campbell Scott, Hawley Carmel, Wong Germaine, Lim Wai H

Abstract excerpt

Deceased donor kidney allocation relies on HLA compatibility at the antigen level, as optimal matching reduces the risk of acute rejection. Whether HLA allele-level mismatches improve, the prediction of acute rejection after transplantation remains unclear. Using data from the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) from 2017 to 2020, HLA antigenic and allelic mismatches between...

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Topics

Humans
Kidney Transplantation
Graft Rejection
HLA Antigens
Alleles
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Histocompatibility Testing

Middle Aged

Australia

Adult

New Zealand

Registries

Transplant Recipients

Source

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Identifiers

PMID: 40193197
DOI: 10.1111/tan.70163
PMCID: PMC11975158

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