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Article

Crystal structure of MexZ, a key repressor responsible for antibiotic resistance in Pseudomonas aeruginosa.

Journal of structural biology - 1 Dec 2010

Alguel Yilmaz, Lu Duo, Quade Nick, Sauter Sebastian, Zhang Xiaodong

Abstract excerpt

Pseudomonas aeruginosa is responsible for around 10% of all hospital-acquired infections and the single most important pathogen of cystic fibrosis lungs. P. aeruginosa has high intrinsic and acquired antibiotic resistance, due to the extrusion of antibiotics by multidrug efflux pumps. The gene regulator MexZ controls the expression of mexXY, the efflux pump responsible for resistance to many drugs that are used...

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Share to Bacterial Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20691272
DOI: 10.1016/j.jsb.2010.07.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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