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Plasma biomarker trajectories: Impact of AD genetic risk and clinical progression

1 Jan 2025

Abstract excerpt

Abstract INTRODUCTION We examined long‐term plasma biomarker trajectories among participants who were cognitively unimpaired and primarily middle aged at baseline and whether trajectories differed by Alzheimer's disease (AD) genetic risk and among those who developed cognitive impairment. METHODS Plasma amyloid beta (Aβ)42/Aβ40, phosphorylated tau (p‐tau)181, neurofilament light chain (NfL), glial fibrillary...

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PMID: 40151521
DOI: 10.1002/dad2.70081

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