Article
A modern heart transplant rejection surveillance protocol utilizing cell-free DNA: A single-center experience
2 Mar 2024
Abstract excerpt
BACKGROUND: Endomyocardial biopsy (EMBx) is considered the gold standard for rejection monitoring after heart transplantation; however, it is invasive and histologic interpretation has limitations. Sensitive blood biomarkers, including donor-derived cell-free DNA (dd-cfDNA), have emerged to decrease EMBx frequency. METHODS: We retrospectively reviewed data on 237 patients who underwent heart transplantation at...
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