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Utility of Plasma Cell-free Chromatin Immunoprecipitation to Detect Cardiac Allograft Rejection

2025-03-05

Abstract excerpt

<h4>Background</h4> Antibody-mediated rejection (AMR) remains the major risk factor for allograft loss across all solid organ transplantation. Unfortunately, its diagnosis relies on biopsy, an invasive gold standard that often sample unaffected allograft tissue leading to missed diagnosis. Plasma donor-derived cell-free DNA (dd-cfDNA) is noninvasive biomarker that has high sensitivity but low specificity for AMR d...

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Literature Corpus work
8ddd1c42-9081-5622-8f85-f977adefd123
DOI
10.1101/2025.03.04.25323391
Open publication

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Utility of Plasma Cell-free Chromatin Immunoprecipitation to Detect Cardiac Allograft RejectionDOI 10.1101/2025.03.04.25323391
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