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Genome profiling with targeted adaptive sampling long-read sequencing for pediatric leukemia

28 Aug 2024

Abstract excerpt

Genome profiling tests for multiple genes are essential in the treatment of leukemia, facilitating precise diagnosis, risk stratification, and identification of therapeutic targets. Targeted capture sequencing with a next-generation sequencer (NGS) is already in use for clinical cancer genome profiling tests [ 1 ]. However, several limitations remain to this approach, including the inferior capability for...

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PMID: 39198403
DOI: 10.1038/s41408-024-01108-5

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