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Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes

24 Mar 2025

Abstract excerpt

Zearalenone (ZEN) is an estrogenic mycotoxin (‘mycoestrogen’) that contaminates global grain crops leading to detectable concentrations of ZEN and its metabolites, including the synthetic version alpha-zearalanol (ZER), in human populations. Despite in vitro and in vivo animal evidence of endocrine disruption by ZEN, there has been limited investigation in humans.

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PMID: 40126888
DOI: 10.1289/ehp14478

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