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Article

Maternal APOE ε2 as a possible risk factor for elevated prenatal Pb levels.

Environmental research - 1 Nov 2024

Palir Neža, Stajnko Anja, Mazej Darja, France Štiglic Alenka, Rosolen Valentina, Mariuz Marika, Ronfani Luca, Snoj Tratnik Janja, Runkel Agneta Annika, Tursunova Veronika, Marc Janja, Prpić Igor, Špirić Zdravko, Barbone Fabio, Horvat Milena, Falnoga Ingrid

Abstract excerpt

Lead (Pb) is a global contaminant associated with multiple adverse health effects. Humans are especially vulnerable during critical developmental stages. During pregnancy, exposure to Pb can occur through diet and release from maternal bones. Apolipoprotein E gene (APOE) variants (ɛ2, ɛ3, ɛ4 alleles) may influence sex steroid hormones, bone metabolism, and Pb kinetics. We examined the interplay among maternal...

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Identifiers

PMID: 38992759
DOI: 10.1016/j.envres.2024.119583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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