Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating the causal relationships between mitochondrial proteins and dementia with Lewy bodies.

Journal of Alzheimer's disease : JAD - 1 May 2025

Ye Jingna, Dai Xuelian, Zhang Canwen, Duan Zhihui, Zhou Guoqing, Wang Juan

Abstract excerpt

BackgroundDisruptions in mitochondrial function have been implicated in various neurodegenerative diseases. However, the specific role of mitochondrial proteins in the pathogenesis of dementia with Lewy bodies (DLB) remains poorly understood.ObjectiveThis study aims to investigate potential causal relationships between mitochondrial proteins and DLB risk using Mendelian randomization (MR) analysis.MethodsCausal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lewy Body Disease

Share to Mendelian Randomization Analysis

Share to Mitochondrial Proteins

Source

Identifiers

PMID: 40111912
DOI: 10.1177/13872877251328882

Genes

C1QBP
GLRX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the causal relationships between mitochondrial proteins and dementia with Lewy bodies.PMID 40111912Read ↗

Mitochondria‐Related Genome‐Wide Mendelian Randomization Identifies Putatively Causal Genes for Neurodegenerative DiseasesSemantic proximity Read ↗

Causal links between mitophagy and Alzheimer’s disease: a Mendelian randomization studySemantic proximity Read ↗

Causal association between mitochondrial function and psychiatric disorders: Insights from a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Undetected Association Between Fatty Acids and Dementia with Lewy Bodies: A Bidirectional Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

Exploring the causal effects of serum lipids and lipidomes on lewy body dementia: a Mendelian randomization study.Semantic proximity Read ↗

A Mendelian randomization study identifies proteins involved in neurodegenerative diseasesSemantic proximity Read ↗

Integrative Multi-Omics Mendelian Randomization Highlights Causal Autophagy-Related Genes for Amyotrophic Lateral Sclerosis.Semantic proximity Read ↗

Mendelian randomization of plasma proteomics identifies novel ALS-associated proteins and their GO enrichment and KEGG pathway analysesSemantic proximity Read ↗

Associations of environmental factors with neurodegeneration: An exposome-wide Mendelian randomization investigationSemantic proximity Read ↗

Mitochondrial dysfunction gene expression, DNA methylation, and inflammatory cytokines interaction activate Alzheimer’s disease: a multi-omics Mendelian randomization studySemantic proximity Read ↗

Investigating the genetic association of mitochondrial DNA copy number with neurodegenerative diseasesSemantic proximity Read ↗

Elevated serum LDL-C increases the risk of Lewy body dementia: a two-sample mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.