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Article

Undetected Association Between Fatty Acids and Dementia with Lewy Bodies: A Bidirectional Two-Sample Mendelian Randomization Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2024

Zhai Weijie, Zhao Anguo, Wei Chunxiao, Xu Yanjiao, Cui Xinran, Zhang Yan, Meng Lingjie, Sun Li

Abstract excerpt

Background: Although observational studies indicated connections between fatty acids (FAs) and Alzheimer's disease and dementia, uncertainty persists regarding how these relationships extend to dementia with Lewy bodies (DLB). Objective: To explore the potential causal relationships between FAs and the development of DLB, thus clarifying these associations using genetic instruments to infer causality. Methods: We...

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PMID: 38995791
DOI: 10.3233/JAD-240267

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