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Article

Association Between Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) Polymorphisms and Risk of Ankylosing Spondylitis: A Meta-analysis.

Medical science monitor : international medical journal of experimental and clinical research - 30 May 2017

Wang Weiming, Meng Xiantao, Liu Yupeng, Ma Xiaojun, Zhang Qian, Li Chunhui, Li Chenye, Ren Liubao

Abstract excerpt

BACKGROUND Ankylosing spondylitis (AS) is a chronic autoimmune disease that involves the imbalance of peripheral tolerance possibly caused by the negative signal of activated T cells. The polymorphisms in the human protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene have been pointed out to be related to the pathogenesis of AS, but conclusions over this issue remain contradictory. We attempted to give...

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Identifiers

PMID: 28555069
DOI: 10.12659/msm.901083
PMCID: PMC5461884

Genes

PTPN22

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Association Between Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) Polymorphisms and Risk of Ankylosing Spondylitis: A Meta-analysis.PMID 28555069Read ↗

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