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Article

Synergistic effect of LEP and LEPR gene polymorphism on body mass index in a Chinese population.

Obesity research & clinical practice - 1 Dec 2013

Lu Jin, Zou Dajin, Zheng Longyi, Chen Guangchun, Lu Jian, Feng Zhengkang

Abstract excerpt

Both leptin (LEP) and leptin receptor (LEPR) are important in the regulation of body weight. In this study, we evaluated the individual and combined effects of a polymorphic microsatellite marker in the LEP gene 3' flanking region and two polymorphisms (Lys109Arg and Lys656Asn) of the LEPR gene on metabolic markers for obesity in a Chinese population. The genotypes of polymorphisms in LEP and LEPR gene were...

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Source

Identifiers

PMID: 24308887
DOI: 10.1016/j.orcp.2012.06.007

Genes

LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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