Telomere Shortening and Its Association with Cell Dysfunction in Lung Diseases

Abstract excerpt

Telomeres are localized at the end of chromosomes to provide genome stability; however, the telomere length tends to be shortened with each cell division inducing a progressive telomere shortening (TS). In addition to age, other factors, such as exposure to pollutants, diet, stress, and disruptions in the shelterin protein complex or genes associated with telomerase induce TS. This phenomenon favors cellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mesenchymal stem cell research
• Share to Telomeres, Telomerase, and Senescence