The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications

Abstract excerpt

Telomeres are distal chromosome regions associated with specific protein complexes that protect the chromosome against degradation and aberrations. Telomere maintenance capacity is an essential indication of healthy cell populations, and telomere damage is observed in processes such as malignant transformation, apoptosis, or cell senescence. At a cellular level, telomere damage may result from genotoxic stress,...

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