Article
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice.
The ocular surface - 1 Jul 2025
Okada Yuka, Sumioka Takayoshi, Iwanishi Hiroki, Yasuda Shingo, Zhang Jianhua, Yuan Yong, Liu Chia-Yang, Whei-Yang Kao Winston, Saika Shizuya
Abstract excerpt
PURPOSE: To the best of our knowledge, no reports have been published on the long-term changes in corneal tissue during the course of neuroparalytic keratopathy caused by destruction of the ophthalmic nerve in experimental animals. To bridge this research gap, we investigated the histopathology of the cornea in mice 3, 12, and 24 months after coagulation of the ophthalmic nerve. METHODS: Nerves were severely...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.