Article

Pitx2-associated early-onset glaucoma alters corneal innervation and sensory function in a sex-specific manner

2026-05-01

Abstract excerpt

<h4>Purpose</h4> Pitx2-associated developmental glaucoma is characterized by anterior segment dysgenesis, ocular hypertension, and optic neuropathy. Its consequences for corneal sensory innervation remain poorly understood. We investigated whether this disease alters corneal nerve structure and sensory function in a sex-dependent manner. <h4>Methods</h4> Male and female Pitx2 egl1/egl1 and Pitx2 +/+ mice were...

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Literature Corpus work: 51c643ca-41b5-5036-987a-66aa58d85157
DOI: 10.64898/2026.04.28.721459

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