Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Embryonic exposure of estrogen and BPA in zebrafish leads to ADHD-like and ASD-like phenotypes, respectively.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Mar 2025

Shen Qiaosen, Zhao Feng, Zhang Na, Zheng Ling, Su Dongmei, Qian Yongyi, Xin Liu, Mingxia Sun, Hongxu Zhang, Chen Fangyi, Qiu Wenhui, Liu Dong

Abstract excerpt

Exposure to the estrogenic pollutant bisphenol A (BPA) during pregnancy and early childhood is a risk factor for numerous neurodevelopmental and psychiatric disorders in humans. To understand why early BPA exposure is associated with attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), we have analyzed a series of zebrafish behaviors, neurodevelopmental process, and gene expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase
Share to Attention Deficit Disorder with Hyperactivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Autism Spectrum Disorder

Share to Benzhydryl Compounds

Share to Estradiol

Share to Estrogens

Share to GABAergic Neurons

Share to Phenols

Source

Identifiers

PMID: 40020986
DOI: 10.1016/j.pnpbp.2025.111293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Embryonic exposure of estrogen and BPA in zebrafish leads to ADHD-like and ASD-like phenotypes, respectively.PMID 40020986Read ↗

Does Bisphenol A Confer Risk of Neurodevelopmental Disorders? What We’ve Learned from Developmental Neurotoxicity Studies in Animal ModelsSemantic proximity Read ↗

Postnatal maternal care moderates the effects of prenatal bisphenol exposure on offspring neurodevelopmental, behavioral, and transcriptomic outcomesSemantic proximity Read ↗

Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish.Semantic proximity Read ↗

Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2.Semantic proximity Read ↗

Structure-based developmental toxicity and ASD-phenotypes of bisphenol A analogues in embryonic zebrafish.Semantic proximity Read ↗

Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71.Semantic proximity Read ↗

Male autism spectrum disorder is linked to brain aromatase disruption by prenatal BPA in multimodal investigations and 10HDA ameliorates the related mouse phenotype.Semantic proximity Read ↗

Enduring autism-like phenotypes and deregulated hypothalamic prosocial peptides after early-life exposure to indoor flame retardants in male C57BL/6 mice.Semantic proximity Read ↗

Gene-Environment Interactions in Autism Spectrum Disorders: The Role of Bisphenol A in Modulating Genetic Susceptibility.Semantic proximity Read ↗

Estradiol modulates neuronal network hyperexcitability in select NDD risk genesSemantic proximity Read ↗

Ethanol exposure model in zebrafish causes phenotypic, behavioral and gene expression changes that mimic Fetal Alcohol Spectrum Disorders in human birth cohortsSemantic proximity Read ↗

Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.