The impact of the CACNB2 Rs11013860 polymorphism on grey matter volume and brain function in bipolar disorder.

doi:10.1186/s12888-025-06611-y

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Article

The impact of the CACNB2 Rs11013860 polymorphism on grey matter volume and brain function in bipolar disorder.

BMC psychiatry - 27 Feb 2025

Cheng Xiaofei, Yang Qian, Zhang Yamin, Zhang Mengmeng, Yu Hua, Ni Peiyan, Li Xiaojing, Li Mingli, Li Tao

Abstract excerpt

BACKGROUND: Recent genome-wide association studies have linked voltage-gated calcium channel genes to bipolar disorder (BD), in which CACNB2 gene rs11013860 is respectively reported. Less is known, though, about how precisely its polymorphism affects both the structure and function of the brain. METHODS: 173 BD patients and 207 healthy controls (HCs) were underwent structural and functional magnetic resonance...

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PMID: 40016690
DOI: 10.1186/s12888-025-06611-y
PMCID: PMC11866725

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CACNB2

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