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Roles of Sirtuins in Cardiovascular Diseases: Mechanisms and Therapeutics

27 Feb 2025

Abstract excerpt

Cardiovascular diseases (CVDs) are experiencing a rapid surge and are widely recognized as the leading cause of mortality in the current aging society. Given the multifactorial etiology of CVDs, understanding the intricate molecular and cellular mechanisms is imperative. Over the past 2 decades, many scientists have focused on Sirtuins, a family of nicotinamide adenine dinucleotide-dependent deacylases. Sirtuins...

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PMID: 40014680
DOI: 10.1161/circresaha.124.325440

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