Identification of glyoxalase A in group B Streptococcus and its contribution to methylglyoxal tolerance and virulence

Abstract excerpt

ABSTRACT Group B Streptococcus (GBS) is a Gram-positive pathobiont that commonly colonizes the gastrointestinal and lower female genital tracts but can cause sepsis and pneumonia in newborns and is a leading cause of neonatal meningitis. Despite the resulting disease severity, the pathogenesis of GBS is not completely understood, especially during the early phases of infection. To investigate GBS factors...

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