Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Assessment of Streptococcus agalactiae Genes Required for Survival in Human Whole Blood and Plasma.

Infection and immunity - 18 Sept 2020

Zhu Luchang, Yerramilli Prasanti, Pruitt Layne, Ojeda Saavedra Matthew, Cantu Concepcion C, Olsen Randall J, Beres Stephen B, Waller Andrew S, Musser James M

Abstract excerpt

Streptococcus agalactiae (group B streptococcus, or GBS) is a common cause of bacteremia and sepsis in newborns, pregnant women, and immunocompromised patients. The molecular mechanisms used by GBS to survive and proliferate in blood are not well understood. Here, using a highly virulent GBS strain and transposon-directed insertion site sequencing (TraDIS), we performed genome-wide screens to discover novel GBS...

Topics

Bacteremia
Bacterial Proteins
Genes, Bacterial
Genetic Fitness
Genome, Bacterial
Humans
Microbial Viability
Mutagenesis, Insertional
Mutation
Streptococcal Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Streptococcus agalactiae

Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 32747604
DOI: 10.1128/IAI.00357-20
PMCID: PMC7504961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Assessment of Streptococcus agalactiae Genes Required for Survival in Human Whole Blood and Plasma.PMID 32747604Read ↗

Genome-wide identification of genes required for fitness of group A Streptococcus in human blood.Semantic proximity Read ↗

Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits.Semantic proximity Read ↗

The Streptococcus agalactiae Stringent Response Enhances Virulence and Persistence in Human BloodSemantic proximity Read ↗

Pan-GWAS of Streptococcus agalactiae Highlights Lineage-Specific Genes Associated with Virulence and Niche AdaptationSemantic proximity Read ↗

Identification of glyoxalase A in group B Streptococcus and its contribution to methylglyoxal tolerance and virulenceSemantic proximity Read ↗

Pan-GWAS of <i>Streptococcus agalactiae</i> highlights lineage-specific genes associated with virulence and niche adaptationSemantic proximity Read ↗

Identification of Glyoxalase A in Group B <i>Streptococcus</i> and its contribution to methylglyoxal tolerance and virulenceSemantic proximity Read ↗

Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategies.Semantic proximity Read ↗

Genome-Wide Identification of Essential Genes in the Invasive <i>Streptococcus anginosus</i> StrainSemantic proximity Read ↗

MrvR, a Group B <i>Streptococcus</i> Transcription Factor that Controls Multiple Virulence TraitsSemantic proximity Read ↗

Dual RNA sequencing of group B Streptococcus-infected human monocytes reveals new insights into host–pathogen interactions and bacterial evasion of phagocytosisSemantic proximity Read ↗

The Transcriptome of the Nosocomial Pathogen Enterococcus faecalis V583 Reveals Adaptive Responses to Growth in BloodSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.