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Article

Global MicroRNA Profiling of HSV-1 Infected Cornea Identifies miR-329 as a Novel Regulator of Virus Infection

24 Feb 2025

Abstract excerpt

Purpose: Although the mechanisms underlying herpes simplex virus type-1 (HSV-1) ocular infection have been extensively studied, the role of host microRNAs (miRNAs) in the pathobiology of herpetic keratitis (HK) is not well understood. The aim of this study was to identify endogenous miRNA regulators involved in the progression of HSV-1 ocular infection. Methods: C57BL/6 mice were infected with HSV-1 strain McKrae...

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PMID: 39992671
DOI: 10.1167/iovs.66.2.61

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