A novel miRNA produced during lytic HSV-1 infection is important for efficient replication in tissue culture.

doi:10.1007/s00705-012-1345-4

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Article

A novel miRNA produced during lytic HSV-1 infection is important for efficient replication in tissue culture.

Archives of virology - 1 Sept 2012

Munson Daniel J, Burch April D

Abstract excerpt

The influence of miRNAs on the host-pathogen environment is largely unknown and under intensive investigation. Whether produced by the pathogen or by the host cell, these miRNAs will sculpt the intracellular landscape, as their activity will ultimately affect levels of target proteins. Using a high-throughput sequencing approach, we identified 19 novel small RNAs produced during the early hours of herpes simplex...

Topics

Animals
Blotting, Northern
Cell Line
Epithelial Cells
Gene Expression Profiling
Genetic Complementation Test
Herpesvirus 1, Human
High-Throughput Nucleotide Sequencing
Host-Pathogen Interactions
Humans
MicroRNAs
Mutation
RNA, Viral
Reverse Transcriptase Polymerase Chain Reaction
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 22661375
DOI: 10.1007/s00705-012-1345-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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