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Article

Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture.

Journal of virology - 1 Jun 2013

Flores Omar, Nakayama Sanae, Whisnant Adam W, Javanbakht Hassan, Cullen Bryan R, Bloom David C

Abstract excerpt

Herpes simplex virus 1 (HSV-1), a ubiquitous human pathogen, expresses several viral microRNAs (miRNAs). These, along with the latency-associated transcript, represent the only viral RNAs detectable in latently infected neuronal cells. Here, for the first time, we analyze which HSV-1 miRNAs are l...

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Identifiers

PMID: 23536669
DOI: 10.1128/JVI.00504-13
PMCID: PMC3676078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23536669-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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