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SGK1 mediates herpes simplex keratitis via the PI3K/SGK1/ Wnt signaling pathways

12 Dec 2024

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) is a common virus infecting the ocular tissue. It infects eye tissues, such as the eyelid, cornea, and conjunctiva. Corneal HSV-1 infection causes herpes simplex keratitis (HSK), which can induce vision loss. Current treatments for eye infections targeting HSV-1 can led to various sequelae. Antiviral drugs only work during active viral replication, and viral resistance has been...

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PMID: 39674392
DOI: 10.1016/j.cellsig.2024.111566

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