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Herpes Simplex Virus 1 Deregulation of Host MicroRNAs

23 Nov 2018

Abstract excerpt

Viruses utilize microRNAs (miRNAs) in a vast variety of possible interactions and mechanisms, apparently far beyond the classical understanding of gene repression in humans. Likewise, herpes simplex virus 1 (HSV-1) expresses numerous miRNAs and deregulates the expression of host miRNAs. Several HSV-1 miRNAs are abundantly expressed in latency, some of which are encoded antisense to transcripts of important...

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PMID: 30477082
DOI: 10.3390/ncrna4040036

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