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Article

Deep immune profiling of intrahepatic cholangiocarcinoma with CODEX multiplexed imaging

19 Feb 2025

Abstract excerpt

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) may be genomically subclassified by the presence of potentially actionable molecular aberrations, of which pathogenic alterations in isocitrate dehydrogenase (IDH)1 and fibroblast growth factor receptor (FGFR)2 are the most frequently observed. The impact of these molecular alterations on the tumor immune microenvironment remains incompletely understood. METHODS:...

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PMID: 39969434
DOI: 10.1097/hc9.0000000000000632

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