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Immunogenomics of cholangiocarcinoma

16 Nov 2023

Abstract excerpt

The development of cholangiocarcinoma spans years, if not decades, during which the immune system becomes corrupted and permissive to primary tumor development and metastasis. This involves subversion of local immunity at tumor sites, as well as systemic immunity and the wider host response. While immune dysfunction is a hallmark of all cholangiocarcinoma, the specific steps of the cancer-immunity cycle that are...

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PMID: 37972940
DOI: 10.1097/hep.0000000000000688

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