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Roles of Post-Translational Modifications of Transcription Factors Involved in Breast Cancer Hypoxia

1 Feb 2025

Abstract excerpt

BC is the most commonly diagnosed cancer and the second leading cause of cancer death among women worldwide. Cellular stress is a condition that leads to disrupted homeostasis by extrinsic and intrinsic factors. Among other stressors, hypoxia is a driving force for breast cancer (BC) progression and a general hallmark of solid tumors. Thus, intratumoral hypoxia is an important determinant of invasion, metastasis,...

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PMID: 39942749
DOI: 10.3390/molecules30030645

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