Article
MorPhiC Consortium: towards functional characterization of all human genes.
Nature - 1 Feb 2025
Adli Mazhar, Przybyla Laralynne, Burdett Tony, Burridge Paul W, Cacheiro Pilar, Chang Howard Y, Engreitz Jesse M, Gilbert Luke A, Greenleaf William J, Hsu Li, Huangfu Danwei, Hung Ling-Hong, Kundaje Anshul, Li Sheng, Parkinson Helen, Qiu Xiaojie, Robson Paul, Schürer Stephan C, Shojaie Ali, Skarnes William C, Smedley Damian, Studer Lorenz, Sun Wei, Vidović Dušica, Vierbuchen Thomas, White Brian S, Yeung Ka Yee, Yue Feng, Zhou Ting
Abstract excerpt
Recent advances in functional genomics and human cellular models have substantially enhanced our understanding of the structure and regulation of the human genome. However, our grasp of the molecular functions of human genes remains incomplete and biased towards specific gene classes. The Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium aims to address this gap by creating a comprehensive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.